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Increasing the frequency of use, amount of use, or type of drug being used can increase the likelihood of an overdose. Crack cocaine overdoses are often triggered by violent drug dealing or ingestion, and typically lead to seizures and respiratory and cardiac arrest.
The pharmacology of crack is different from cocaine powder, resulting in increased stimulant and sedative effects. Crack addicts often take higher doses of cocaine, and they are likely to experience a higher craving for more cocaine. Crack appears to have a more significant cardiovascular and respiratory depressant effect than cocaine powder.
Plasma levels of metabolites indicate that crack cocaine users more quickly absorb and metabolize the drug. In addition, cocaine acts in many physiological and behavioral systems including the dopaminergic and the limbic system of the brain.
The risk of becoming physically addicted to crack cocaine is thought to be low. Many users report using crack, which causes undesirable effects, without becoming physically addicted. The same is not said about individuals who smoke tobacco or use other drugs, as they may become addicted to other substances.
Many sources claim that crack cocaine is more addictive than powder cocaine. However, there are conflicting studies of the relative addictive potential of crack cocaine compared to powder cocaine. Critics also argue that powder cocaine was created with a purpose – to be inhaled, and therefore might be less harmful than crack cocaine.
I think that the problem is that a half-decent crack-cooking pot is expensive relative to that of a stock pot. Besides, most folks don’t want to go through the hassle of heating up their entire kitchen when all they want to make is a few shots of powder, he adds.
Although the U.S. Sentencing Commission’s report initially recommended parity, that did not go far enough, so the committee was left with little choice but to retain the crack-powder disparity for a decision that must strike a balance between a number of competing interests. At issue are the public safety, the justice system’s ability to offer fair and equal treatment, and the criminal justice system’s ability to efficiently and fairly allocate its resources. Crack is less harmful and addictive than powder cocaine, but it is illegal and receives a harsher sentence because the powder cocaine trade is legal and has powerful and entrenched interests protecting it. In order to arrest and incarcerate more Black men and women, law enforcement agencies have adopted a “zero-tolerance” policy for drugs, leading to a situation where Black men and women are disproportionately and unfairly arrested or charged for drug possession. We need to get crack-cocaine users out of prison, reform the crack-powder sentencing disparity, and better provide treatment to affected individuals. Those are the only three things that will truly save Black lives. Six of the 12 estimates favored any crack cocaine usage over non-use by a 4-fold odds ratio (OR) ranging from 2.8 (95% CI, 1.8-4.4) in Latin America to 5.8 (95% CI, 3.6-9.4) in Asia and the Middle East. New York City was an outlier, reporting higher odds of any crack cocaine use (OR, 1.9; 95% CI, 1.1-3.2) than in any other city. Only one study found a positive association between crack cocaine use and employment, and two did not find any significant association between crack use and employment. Decreased employment is a well-known consequence of crack cocaine use, and its relation to problematic crack use and use disorder is still unclear. 5ec8ef588b
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